GLP-1 medications, like the well-known "Ozempic," have become a phenomenon in the world of weight loss. However, as discovered by plastic surgeons in the USA, these drugs may have an unexpected side effect—accelerated skin aging. According to statistics, about 15.5 million Americans have used these medications, and many were shocked when they consulted plastic surgeons.
Doctors note that the skin and deeper layers of skin in users of "Ozempic" behave unusually. It becomes similar to a "film" or "elastic band" that stretches over time. This phenomenon has been dubbed "Ozempic face," describing the gaunt faces that can result from rapid weight loss. Umbarin Mahmood, a board-certified plastic surgeon in New York, observed signs of "accelerated aging" in her patients, including more pronounced fine lines, sagging cheeks, and skin fragility.
These changes are not limited to the face. Dr. Mahmood also noticed increased tissue laxity in the breasts, abdomen, arms, and thighs of patients taking GLP-1 for weight loss. A recent study published in the Aesthetic Surgery Journal showed that GLP-1 can "turn off" fat-derived stem cells located in the upper dermal layers of the skin. These cells play a crucial role in maintaining youthful skin as they stimulate the production of collagen, elastin, and hyaluronic acid—key components for skin firmness and health.
Thus, while GLP-1 medications may be effective in combating excess weight, it's important to consider their potential impact on skin condition and aging. It might be wise to discuss all the pros and cons with a doctor before starting their use.
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